Profound – an innovative radiofrequency device (shown above) by Syneron Medical, is now “clinically proven to improve facial and neck wrinkles without surgery,” says the results of a newly published clincal trial.

The way it works is by delivering energy directly into the skin’s dermis layer to stimulate elastin, collagen, and hyaluronic acid – and a prior study showed this effect. The results of the new clinical trial have established the optimal treatment parameters for Profound for use on the face and neck.  

Syneron Medical says using its Profound micro-needle-based radiofrequency energy delivery system enables precise, real time, temperature control within the skin – and the study reveals the optimal temperature and duration of temperature for maximum histologic and clinical results in wrinkle and laxity reduction. The treatment adds volume and resiliency to the jawline, neck, jowls, nasolabial folds and cheeks.

The randomized, blinded, 3-arm clinical trial is published in the Dermatologic Surgery Journal, the May 2015 issue. It is by Macrene Alexiades, MD, PhD, and associate clinical professor at Yale University School of Medicine.

The Results

A Profound treatment can produce up to 89% of the laxity improvement results of a surgical facelift – all in one 30 minute treatment.

Alexiades explained, “With these results, we now know for the first time in history precisely how much energy we need to deliver into the dermis and what endpoints to generate the most dramatic results possible without adverse events. In my experience, this is by far the most effective device for dermal volumizing and laxity reduction in a single treatment.”

Shimon Eckhouse, PhD, Chairman of the Board of Directors of Syneron Candela, added, “Profound is at the forefront of a new category of innovative medical aesthetic devices that addresses skin aging in an entirely different way than what is currently available. Consumers want non-surgical procedures that deliver maximum results. With Profound’s technology, physicians are able to consistently achieve this, allowing them to create dramatically younger, smoother and more elastic skin with unprecedented outcomes.”