Debut, a biotech beauty leader, unveiled BeautyORB, an AI-powered innovation engine that provides a new way to discover novel ingredients for best-in-class claims for beauty brands.
 
The genomics-based AI platform has already helped create ingredients addressing inflammation, epidermal barrier repair, and longevity. Brightening, anti-aging, and scalp care ingredients are currently in the pipeline.
 
Joshua Britton, Ph.D, Founder and CEO of Debut, said, 
 
“With our advanced AI platform and understanding of skin biology, we can rapidly create brand new ingredients through computational compound prediction. This allows us to activate specific aspects of skin biology while also discovering new or improved cellular pathways for enhanced clinical claims.”
 
Using BeautyORB, Debut aims to create two biotech ingredients each year.
 
BeautyORB discovers new ingredients by screening 50 billion molecules for their ability to turn on cellular pathways within the skin, a process that has not been possible previously in beauty. 
 
Britton added, 
 
“We don’t have to rely on an array of existing ingredients to test against specific claims, and we don’t have to go into the field to find rare ingredients in plants. All this can be done at the click of a button, cutting out years from the innovation cycle and accessing ingredients that no one has seen before. We can turn on and off molecular pathways differently and use AI to discover what molecules can affect those pathways. The result is a rich, proven, and growing pipeline of novel ingredients with the strongest clinical results for our customers, allowing brands to win on product performance rather than marketing.”
 
Debut’s AI platform has already identified three novel, patented ingredients that achieve the highest beauty standards including scientifically-proven, clinically-tested, and 100% bio-based ingredients that beat existing benchmarks. 

BeautyORB Created Ingredients

• DermCeutical InflammagePRO: Best-in-class for inflammation. Decreases inflammatory markers, supports the skin barrier, and enhances elasticity. 15X better than niacinamide, according to Debut. 

• DermCeutical Barrier RepairPRO: Best-in-class for epidermal barrier repair. Defends the skin against damage from environmental aggressors. 30% better than vitamin C for skin damage repair, Debut said.

• DermCeutical LongevityPRO: Best-in-class for cellular longevity. Decreases markers of cellular senescence and helps maintain healthy skin cells. Debut claims it’s 2X better than vitamin C for skin health. 

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Photo: Billy Economou, BE Studios